Microfluidic Vascular Modeling Platform Solution
One-stop service for microfluidic vascular research
Research on microfluidic vasculature
The Microfluidic Vascular Research Platform (MVRP) launched by Hong Hong Biotech and Cellix is designed for in vitro research using microfluidic wafers to analogize human blood vessels flowing under physiological environment. Blood vessels play an important role in diseases such as thrombosis, inflammation, and atherosclerosis, etc. Utilizing a microfluidic vascular research system can help study the mechanisms of the diseases, evaluation of vascular drugs, and so on.
Working Principle
How does VenaFlux model human blood vessels?
The microcapillaries of the Vena8 Fluoro+ and Vena8 Endothelial+ biochips resemble arteries, veins, and capillaries, allowing for in vitro studies of blood-coagulation factor interactions under shear stress.
What is shear stress?
Blood flows in arteries, veins and capillaries under different shear stresses. Shear stress is the frictional force generated by the flow of blood through a blood vessel - it is the force exerted by the blood on the vessel wall and is expressed in force-area units (usually dyne/cm2).
Job Application
A PC with VenaFlux Assay software is connected to the Mirus Evo pump via USB. the Mirus Evo pump tubing kit connects the Mirus Evo pump to the MultiFlow8, and the MultiFlow8 connecting tubing connects the MultiFlow 8 to the biochip. The biochip is placed in the microenvironment chamber on the microscope stage.
Hong Hong Microfluidic Vascular Research Diversified Package Recommendation
We offer a wide range of microfluidic vascular research instrument packages. Click on the blue fonts to go to the corresponding product page for more information.
Starter Edition
- Mirus Evo Pump with MultiFlow8
- VenaFluxAssay Software for PC
- Wafer Microenvironmental Chamber
- Image Pro Premier
- biochip
Pro version
- Mirus Evo Pump with MultiFlow8
- VenaFluxAssay Software for PC
- Wafer Microenvironmental Chamber
- Image Pro Premier
- biochip
- Zeiss Axio Vert A1 Fluorescent Microscope with Manual Carrier
- Digital Cameras for Image Acquisition: Prime BSI Express
- 1 glass syringe for Mirus Evo pumps
- Power & Cables
- Elite Edition
Elite Edition
- Mirus Evo Pump with MultiFlow8
- VenaFluxAssay Software for PC
- Wafer Microenvironmental Chamber
- Image Pro Premier
- biochip
- Zeiss Axio Observer 7 fluorescent microscope with automatic stage
- Digital Cameras for Image Acquisition: Prime BSI Express
- 1 glass syringe for Mirus Evo pumps
- Power & Cables
Hong Hong Microfluidic Vascular Research Diversified Package Recommendation
- Thrombosis/Platelet Adhesion and Aggregation Shear Flow Experience
- Shear-based cell rolling, adhesion and migration assays were performed on ligand-encapsulated surfaces or endothelial cells for the following studies:
Inflammation:Leukocyte and T-cell adhesion studies in sepsis, statins, and immune disorders
Asthma and allergies:Eosinophil Adhesion Study of Anti-inflammatory, Antihistamine Drugs (e.g., Cetirizine/Levocetirizine-Menglust)
Oncology:Adhesion and transfer of melanoma cells
Bacteria:Adhesion and biofilm formation of Escherichia coli
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