Temperature monitoring solutions for cryogenic liquid nitrogen containers
Proven, reliable performance down to -200 °C for liquid nitrogen tank temperature monitoring
API raw pharmaceuticals, freeze-dried substances and human samples must be transported and stored in the glass phase at the lowest possible temperature. For this purpose, specialized dry liquid nitrogen tanks can be used to maintain temperatures at -196°C using liquid nitrogen (LN2.) Temperature monitoring of cryogenic tanks is not only challenging due to the extremely low temperatures, but also requires more complex operational procedures such as pre-cooling and refilling with LN2.
Importance of temperature monitoring of liquid nitrogen tanks
Temperature testing during storage and transportation in liquid nitrogen tanks is very important for raw pharmaceuticals, freeze-dried substances and human subjects, and its importance is mainly realized in the following aspects:
1
Quality Assurance
These biological samples or drugs are extremely sensitive to temperature and may change or even lose their activity when the temperature fluctuates or exceeds the range. Through temperature monitoring, we can ensure that the temperature of the samples or drugs is maintained at a stable level during the storage and transportation process, thus safeguarding the quality.
2
Guaranteeing security
Some biomarkers or pharmaceuticals are extremely sensitive to temperature fluctuations. Excessively high or low temperatures may affect their safety or even lead to product contamination or hazards. Through temperature monitoring, temperature anomalies can be detected and avoided in time to ensure product safety.
3
Compliance Requirements
The storage and transportation of some pharmaceuticals and biosensors are subject to stringent regulations and standards, which often require temperature monitoring and recording. Temperature monitoring ensures compliance with regulatory requirements and avoids fines or other legal issues.
4
Retrospective liability
When a product quality problem occurs, temperature monitoring can trace the temperature condition during the entire storage and transportation process, help to determine the responsibility and cause, and then improve storage and transportation management to reduce the possibility of quality problems.
Importance of temperature monitoring of liquid nitrogen tanks
Temperature testing during storage and transportation in liquid nitrogen tanks is very important for raw pharmaceuticals, freeze-dried substances and human subjects, and its importance is mainly realized in the following aspects:
- Extreme low temperature
The very low temperature of liquid nitrogen, typically around -196 degrees Celsius, means that temperature monitoring equipment and sensors need to be able to function and maintain accuracy at extremely low temperatures.
- Sealing performance
Liquid nitrogen tanks are usually hermetically sealed, which means that the temperature monitoring equipment needs to be able to be safely placed in the tank and the sealing of the tank must not be compromised in a way that would affect the accuracy of the temperature monitoring.
- Data Transfer
When monitoring temperature in liquid nitrogen tanks, there is a need to ensure that temperature data can be reliably transmitted, and consideration needs to be given to maintaining the stability of data transmission, especially in special transportation environments.
- Equipment Reliability
Temperature monitoring equipment operating in extreme environments needs to be highly reliable and able to operate stably for long periods of time without failure, which poses a challenge to the design and selection of the monitoring equipment itself.
Honghong meets the pharmaceutical industry's standard
Liquid Nitrogen Tank Transportation and Storage Temperature Monitoring Solutions
In order to realize temperature monitoring, you can consider using temperature sensor/temperature probe or temperature recorder, which will be placed in the liquid nitrogen tank and stored or transported together with the samples, and continuously record the temperature during the whole process. During the storage and transportation process, you can use liquid nitrogen special & stable temperature probe and cloud platform technology to realize real-time monitoring and recording of temperature, and alert the relevant personnel to take timely measures when problems or abnormalities occur.
HH-LIBERO CE
PDF/Bluetooth temperature logger with external probe
- Temperature recorder with external probe, the temperature probe is introduced into the liquid nitrogen tank.
- Suitable for low-temperature containers, customized temperature probe for liquid nitrogen tank applications
- PDF/Bluetooth Temperature Recorder
- Complies with GAMP® 5 and FDA 21CFR Part 11 standards.
- Coin cell battery powered, IATA compliant, safe for air transportation
- Temperatures down to -200 °C
- Configuration via USB or Bluetooth (Mobile App)
- Multiple use (3 year battery life)
- Read PDF reports via computer USB or Bluetooth (mobile app).
- Detailed analysis with elproVIEWER, compatible with liberoMANAGER
- IQ-OQ templates for easy customer validation
- Free calibration certificate
- Provide guidance and recommendations for installation on liquid nitrogen tanks
HH-LIBERO GE
Temperature logger with external probe for real-time transmission.
- Temperature recorder with external probe, the temperature probe is introduced into the liquid nitrogen tank.
- Suitable for low-temperature containers, customized temperature probe for liquid nitrogen tank applications
- Temperature logger with real-time transmission
- Complies with GAMP® 5 and FDA 21CFR Part 11 standards.
- Dry-battery powered, IATA compliant, safe for air transportation
- Temperatures down to -200 °C and position and tilt can be measured
- Configuration via web interface
- Multiple use (14 month battery life)
- Real-time automatic readout and alarms via elproCLOUD cloud platform
- Detailed analysis via elproCLOUD cloud platform, compatible with liberoMANAGER
- IQ-OQ templates for easy customer validation
- Free calibration certificate
- Provide guidance and recommendations for installation on liquid nitrogen tanks
HH-LIBERO GF ext
Temperature logger with external probe for real-time transmission.
Suitable for refrigeration, ultra-low temperature and liquid nitrogen applications.
- Temperature logger with external probe, temperature probe into liquid nitrogen tank, freezer, dry ice
- Suitable for low-temperature containers, customized temperature probe for liquid nitrogen tank applications
- Real-Time Temperature Logger for Refrigeration, Freezing, Ultra Low Temperature and Liquid Nitrogen Applications
- Complies with GAMP® 5 and FDA 21CFR Part 11 standards.
- Temperatures down to -200 °C and position and tilt can be measured
- Includes a lithium metal battery to ensure operation in low temperature environments down to -35°C.
- Configuration via web interface
- Multiple use (14 month battery life)
- Real-time automatic readout and alarms via elproCLOUD cloud platform
- Detailed analysis via elproCLOUD cloud platform, compatible with liberoMANAGER
- IQ-OQ templates for easy customer validation
- Free calibration certificate
- Provide guidance and recommendations for installation on liquid nitrogen tanks
Completion of aviation safety certification for safe air transportation
All of the liquid nitrogen tank transportation and storage temperature monitoring products provided by Honghong have obtained the aviation safety appraisal report (Cargo Transportation Condition Appraisal Certificate) from Beijing DGM and Shanghai Institute of Chemical Technology, and can be safely transported by air.
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